Search This Blog

Monday, June 8, 2020

Decision Rule - King's College Criteria for Acetaminophen Toxicity


King’s College Criteria for Acetaminophen Toxicity

-Arterial pH <7.30  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  [No/Yes]
-INR >6.5 (PT >100 seconds) . . . . . . . . . . . . . . . . . . . . . . . .  [No/Yes]
-Creatinine 3.4 mg/dL (300 µmol/L) . . . . . . . . . . . . . . . . . . . . [No/Yes]
-Grade III or IV hepatic encephalopathy  . . . . . . . . . . . . . . . .  [No/Yes]

The presence of any of the above should prompt referral and possible transfer to a center capable of liver transplantation.

Other predictors of a poor prognosis without transplant:

-Lactate >3.5 mmol/L after fluid resuscitation (<4 hours)  . . .  [No/Yes]
-Lactate >3 mmol/L after full fluid resuscitation (12 hours) . .  [No/Yes]
-Phosphate >3.75 mg/dL (1.2 mmol/L) at 48-96 hours . . . . .  [No/Yes]


No comments:

Post a Comment

Hunt & Hess Classification of Subarachnoid Hemorrhage (SAH)

Hunt & Hess Classification of Subarachnoid Hemorrhage (SAH) Classifies severity of SAH to predict mortality based on signs and symptom...